Promethazine HCl Oral Answer may possibly reduced seizure threshold. It should be employed with warning in folks with seizure Diseases or in people who are applying concomitant prescription drugs, including narcotics or neighborhood anesthetics, which may also impact seizure threshold.
Codeine has very good antitussive exercise, Despite the fact that a lot less than that of morphine at equal doses. It truly is used in choice to morphine, for the reason that Unwanted side effects are infrequent at the standard antitussive dose of codeine.
Narcotics may deliver adverse reactions which can obscure the clinical training course of patients with head injuries.
Antihistamines are contraindicated for use in the treatment method of lower respiratory tract signs and symptoms, like bronchial asthma.
Stay away from using Promethazine HCl and Codeine Phosphate Oral Alternative in adolescents twelve to 18 a long time of age who produce other possibility things that could improve their sensitivity to your respiratory depressant results of codeine.
For prescriptions where a measuring gadget is not really presented, a pharmacist can provide an appropriate calibrated measuring unit and can offer Guidelines for measuring the right dose.
If this SPL incorporates inactivated NDCs mentioned through the FDA initiated compliance motion, they will be specified as such.
Low blood pressure level. A sudden fall in blood pressure can take place in a lot of people through therapy with Promethazine Hydrochloride and Codeine Phosphate click here Oral Option which might result in you to truly feel dizzy, faint, lightheaded, or weak, especially when you arise (orthostatic hypotension). Your danger of getting this problem might be improved if you take Promethazine Hydrochloride and Codeine Phosphate Oral Solution with sure other medicines that reduce blood pressure.
Symptoms and signs of overdosage with Promethazine HCl range between mild melancholy on the central anxious method and cardiovascular method to profound hypotension, respiratory depression, unconsciousness, and sudden Dying.
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Restricted details suggest that utilization of promethazine hydrochloride in the course of labor and delivery doesn't have an considerable impact on the duration of labor or delivery and doesn't raise the threat of need to have for intervention inside the new child.
When provided concomitantly with Promethazine HCl Oral Alternative, the dose of barbiturates really should be minimized by no less than a single-50 %, along with the dose of narcotics ought to be minimized by one-quarter to one-fifty percent. Dosage should be individualized. Abnormal amounts of promethazine HCl relative to a narcotic may perhaps produce restlessness and motor hyperactivity during the individual with discomfort; these indicators generally vanish with adequate control of the ache.
Lactation At the least one particular Demise was described in the nursing toddler who was subjected to substantial amounts of morphine in breast milk as the mother was an ultra-immediate metabolizer of codeine.
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